In this study we developed new ceramic compositions with competent mechanical properties at highly porous state. Strontium(Sr) doped hardystonite(Ca 2 ZnSi 2 O 7 ) powder was mixed with aluminium oxide(Al 2 O 3 ) powder of different weight fractions(0, 5, 10, 15 and 30wt%) and the resultant ceramic labelled as SH, SH5, SH10, SH15 and SH30, respectively. Polymer sponge method was used to prepare the different ceramic scaffolds. Developed ceramics showed a unique microstructure consisted of three phases of (1) Sr doped Ca 2 ZnSi 2 O 7 grains, (2) a wetting glass phase at the grain boundaries and (3) submicron crystals of ZnAl 2 O 4 (Gahnite) embedded in the glass phase. The scaffolds at 85% porosity, average pore size of 400µm and ∼100% interconnectivity between the pores, achieved a compressive strength range of 0.8–4.1MPa, modulus range of 48–173MPa and failure strain range of 0.4–3.1%. In-vitro cytotoxicity results not only indicated the biocompatibility of these scaffolds, but also their positive effects on inducing the proliferation of primary human osteoblasts (HOBs).