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GPX1 encoding the enzyme glutathione peroxidase 1 (GPX1) and hOGG1 encoding the 8-oxoguanine glycosylase 1 (OGG1) may counteract oxidative stress and resulting DNA damage associated with lifestyle-related exposures. We examined whether the polymorphisms GPX1 Pro 198 Leu and OGG1 Ser 326 Cys or low erythrocyte GPX enzyme activity in pre-diagnostic blood samples are associated with colorectal...
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