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Studies have been performed in our laboratory to determine the preneoplastic and neoplastic potential of cells from morphologically different types of transformed foci. Transformed foci induced by 3-methylcholanthrene in BALB/c-3T3 cells were classified into five morphologically distinct types based on size (2-3, 3-4 and >4 mm in diameter), invasiveness (smooth vs. invading margins) and other properties...
A large number of workers are potentially exposed to cadmium during mining and processing. Therefore, there is a concern regarding the potential carcinogenic hazards of cadmium to exposed workers. Studies have been performed to determine if cadmium chloride (CdCl 2 ) can induce morphological cell transformation, DNA from CdCl 2 -induced transformed cells can transform other mammalian...
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