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Tyrosine phosphorylation of the nicotinic acetylcholine receptor (AChR) may be involved in AChR desensitization and clustering. Torpedo AChR γ-subunit is phosphorylated at Tyr 365 . Using overlapping synthetic peptides, we have precisely mapped the epitopes of five anti-γ-subunit monoclonal antibodies (mAbs) and found that the epitope(s) for the mAbs 154, 165 and 168 (γ365-370)...
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