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NFκB, a nuclear transcription factor, was induced in the brain nuclear fraction of naive rats after an acute injection of ethanol, 2 g/kg. In contrast, rats which had been chronically alcoholised showed the constitutively active NFκB-like complex only after a further acute dose of ethanol. Hepatic nuclear fractions did not exhibit the specific NKκB-like complex during the first 45 min after acute...
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