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Retinoic acid receptor (RAR) γ gene is expressed in the precartilaginous cells during chondrogenesis in mouse embryos, but the role of the gene products is still unclear. To examine the role during chondrogenesis, we isolated mesenchymal cells from the limb bud of mouse embryos and exposed them to antisense RAR γ-1 oligodeoxynucleotide in micromass culture. The antisense oligodeoxynucleotide inhibited...
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