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α-Synuclein is the major filamentous constituent of Lewy bodies found in Parkinson’s disease (PD). The amyloid formation of α-synuclein was significantly facilitated by oxidized glutathione (GSSG) as the lag period of the aggregation kinetics was shortened by 2.5-fold from its absence. Reduced glutathione (GSH), on the other hand, did not influence the lag phase although it increased the final amyloid...
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