Substitutional compounds Cr 1−x Ti x Sb 2 (0≤x≤0.10) were synthesized, and the effect of Ti substitution on transport and thermoelectric properties of Cr 1−x Ti x Sb 2 were investigated from 7 to 310K. The results indicated that the temperature dependence of electrical resistivity and thermopower ǀSǀ for CrSb 2 did not alter significantly after substitution. However, the magnitudes of the resistivity and thermopower of Cr 1−x Ti x Sb 2 decreased monotonically with increasing Ti content owing to an increase in electron concentration indirectly caused by Ti substitution for Cr. Experiments also showed that the low-temperature lattice thermal conductivity of Cr 1−x Ti x Sb 2 generally decreased with increasing Ti content, which could originate from an enhancement of phonon scattering by increased number of Ti atoms. As a result, the figures of merit, ZT, of lightly-doped Cr 1−x Ti x Sb 2 (x=0.03) samples was improved at T>∼200K. Specifically, at 310K, the ZT value of Cr 0.97 Ti 0.03 Sb 2 was ∼11% larger than that of CrSb 2 , indicating that thermoelectric properties of CrSb 2 can be improved by an appropriate substitution of Ti for Cr.