Toward searching for illegal drugs, we investigated the pulsed nuclear quadrupole resonance (NQR) response of 14 N in (1R,2S)-(-)-norephedrine, based on the predictions of quantum chemical calculations. Two pairs of spectral lines (ν + =3.089, 3.093MHz and ν − =2.594, 2.608MHz) were observed despite its molecule structure having only a single nitrogen atom. This indicates that the molecular crystal has two nonequivalent nitrogen atoms in the unit cell. The temperature dependence of the NQR frequencies and relaxation properties were investigated for the purpose of accurate remote sensing of the drugs. The NQR frequency shift was approximately 0.23kHz/K around room temperature. The spin-lattice relaxation and spin-phase memory times were 5.2–10.2ms and 0.6–1.5ms, respectively.