The continents of Africa and Asia have the highest number of HIV infected persons in the world. Worldwide there are 42 million and 29.7 million(70%) are in sub Saharan Africa 1 [United Nations AIDS (UNAIDS). Available from: www.unaids.org]. The stigma and discrimination attached to HIV/AIDS are hampering control of the disease. Family life has greatly been disrupted by the pandemic. AIDS causes illness, disability and death as well as severe economic and emotional disruptions to the families. The epidemic is well established in South Africa. The mortality will be doubled over the next five years. 2 A broad range of coercive measures has been considered to be applied internationally in the interest of controlling the spread of HIV. 3 Responsibility of the employers to their HIV/AIDS employees at workplace, choice of termination of pregnancy when a woman is HIV positive, attitude of health care provider to their HIV infected patients, informed consent for taking blood to protect from transmission of infection in a case of accidental prick, and forced resignation from employment, are discussed in this manuscript. The ethical problems are highlighted, and possible solutions recommended.