The separation of platinum (IV) from wastewater across hollow fiber supported liquid membrane was successful in reaching 96% extraction and 88% stripping using 10% (v/v) trioctylmethyl-ammonium chloride (Aliquat 336) as the extractant. The mass transfer resistances were (1/ka) 3.297×104s/cm, (1/km) 0.164×104s/cm, (1/ko) 3.404×104s/cm and (1/K) 6.865×104s/cm. The system was governed by the mass transfer resistance from the liquid-membrane. Response surface methodology was used to qualify and estimate the influence of operating conditions. Predicted model with experimental data were in good agreement at a standard deviation of 1%.