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Studies were undertaken to determine whether a dose of oral Mycobacterium bovis bacillus Calmette–Guérin (BCG) which did not induce skin test reactivity could protect cattle against bovine tuberculosis (TB). Groups of calves (n = 9) were vaccinated by administering 10 8 , 10 7 or 10 6 colony forming units (CFU) of BCG orally or 10 6 CFU subcutaneous (s.c.) BCG. A control...
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