The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Medical imaging techniques are an important element in early detection for many cancers. They are also essential for determining the location, extension and stage of the lesion in diagnosis, for guiding treatment and therapeutic interventions, and for assessing tumour response during and after treatment. Imaging methods range from anatomically based methods (ultrasound, conventional plain X-rays,...
The historical use of chemotherapy relied on the systemic use of cytotoxic agents to disrupt mitosis in rapidly dividing cancer cells, with foreseeable dose-limiting haematological toxicities. Targeted therapies affect specific cellular molecular mechanisms promoting cancer cell survival and proliferation, enabling treatment tailored to specific tumour characteristics. The key pathways include the...
Radiation therapy utilizes high-energy radiation from X-rays, γ-rays, neutrons, electrons, protons and other sources to kill cancer cells and shrink tumours. External-beam radiation therapy (EBRT) is delivered by a machine outside the body, while brachytherapy or internal radiation therapy comes from radioactive material placed in the body near or within the tumour. EBRT is by far the most common...
Cancer is a genetic disease. Most common cancers are caused by acquired mutations in somatic cells. In contrast, specific germline mutations account for rare hereditary cancer syndromes. In general, cancer-associated genes can be divided into two groups: oncogenes and tumour suppressor genes (TSGs). Oncogenes undergo activation and are phenotypically dominant, while TSGs undergo inactivation and are...
Cytotoxic chemotherapy remains an important component of anti-cancer therapy. However, newer ‘targeted agents’ are emerging as more effective agents in certain cancer types as determined by their molecular phenotype.
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.