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Renal dysfunction frequently complicates liver disease and, when present, adversely affects prognosis. While a number of conditions can affect both the liver and the kidney acutely (e.g. paracetamol), many hepatotoxic insults (e.g. alcohol or viral hepatitis) cause more problems associated with cirrhosis. This review focuses mainly on the renal dysfunction associated with this chronic liver damage...
The development of ascites and/or the hepatorenal syndrome in liver disease signifies the beginning of the end of liver function (decompensation). These patients need careful medical management to reverse these abnormalities, and identify any precipitating cause such as sepsis or complication such as spontaneous bacterial peritonitis. Once ascites develops, all patients should be considered for liver...
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