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Chronic liver disease is increasingly common in the UK, and now causes in excess of 5000 deaths per year. The natural history of liver injury is of increasing fibrosis in response to hepatocellular injury, which is usually asymptomatic until decompensation occurs. Up until this point, elevated liver enzyme concentrations are the only indicators of disease. Thorough investigation of abnormal liver...
The most common symptoms of advanced disease, such as pain, nausea and dyspnoea, are readily assessed and often the focus of consultations. However, many prevalent symptoms remain that may be ignored if not specifically sought by the healthcare professional and, unaddressed, these symptoms may have a significant impact on remaining quality of life. This paper will focus on the assessment and management...
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