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To better understand aging women's experience with overactive bladder (OAB) symptoms and the care they receive, with the ultimate goal of improving the quality of care provided to aging women with overactive bladder.Women seen in outpatient female urology clinics were identified by ICD-9 codes for OAB and recruited. Patients with painful bladder syndrome, mixed stress and urge incontinence, prolapse,...
Patients with genitourinary tumors and inferior vena cava thrombus often have large lesions and significant neovascularity. Early division of the renal vein with the in situ thrombus is desirable; however, concerns have been raised regarding tumor spillage and thrombus migration. We describe a novel technique using a stapling device to secure the renal vein during resection of renal tumors associated...
To assess the involvement of estrogen in spermatogenesis, we evaluated the expression of estrogen receptors (ERs) alpha (ERalpha) and beta (ERbeta) in the cryptorchid testes in model rats exposed to flutamide during the fetal stage.Cryptorchid model rats were produced by administering flutamide to pregnant Sprague-Dawley rats. To evaluate the sequential change in the expression of ERalpha and ERbeta...
To test the efficacy and safety of oral L-citrulline supplementation in improving erection hardness in patients with mild erectile dysfunction (ED). L-arginine supplementation improves nitric oxide-mediated vasodilation and endothelial function; however, oral administration has been hampered by extensive presystemic metabolism. In contrast, L-citrulline escapes presystemic metabolism and is converted...
To examine the correlation between the prostate-specific antigen doubling time (PSADT) and overall survival (OS) and among men in the SEARCH database (an older, racially diverse cohort undergoing RP at multiple Veterans Affairs medical centers). Previous studies largely performed at tertiary care centers with relatively young, racially homogenous cohorts found a short PSADT on recurrence after RP...
A 24-year-old male with mixed germ cell tumor after orchiectomy received chemotherapy for abdominal and thoracic lymphadenopathy. Follow-up imaging revealed residual disease in the retroperitoneum as well as thrombus within his inferior vena cava. At surgery, the mass was palpable within the inferior vena cava. After vascular control both proximal and distal to the intraluminal mass, a cavotomy allowed...
Urologists are integrally involved in the management of acute kidney injury (AKI), which is common after renal surgery or secondary to postrenal (obstructive) etiologies. The measurement of serum creatinine is a suboptimal indicator of AKI because it lags behind acute changes in renal function. Recent advances indicate that serum/urine biomarkers will prove useful for early detection of AKI, analogous...
To evaluate the surgical outcome in, and satisfaction with treatment of, patients undergoing epididymectomy for postvasectomy pain syndrome.A total of 49 patients were included. All participants had undergone epididymectomy for chronic epididymal pain from January 2000 to June 2009. Of the 49 patients, 4 had undergone bilateral epididymectomy, and the total number of procedures was 53: 18 in patients...
The discovery of local anesthesia revolutionized urologic surgery. We investigate the evolution of intraurethral anesthesia in urologic surgery beginning in 1884.A review of the literature was performed, reviewing the history of local anesthesia for urologic surgery, with a specific emphasis on intraurethral anesthesia. Using the University of Rochester libraries catalog “Voyager,” a search was performed...
To determine the effect of phospholipase A 2 (PLA 2 ) inhibitors on urothelial cell platelet-activating factor (PAF) production in response to tryptase stimulation.Urothelial cells isolated from normal human ureters were immortalized with the human papillomavirus type 16E6E7 cell line (TEU-2 cells). PLA 2 activity in TEU-2 cells was measured using (16:0, [ 3 H]18:1)...
To compare the safety and efficacy of two different ureteral occlusion devices (stone cone and entrapment net) in preventing retrograde stone migration during ureteroscopic pneumatic lithotripsy. Proximal migration of stone fragments during ureteroscopic lithotripsy is a common problem, especially when the pneumatic lithotripter is used for stone fragmentation.A total of 195 patients with proximal...
To report a retrospective series of proximal ureteral stone ureteroscopies (URS) by a single surgeon, using results presented in a recommended format from the American Urological Association Ureteral Stone Guideline panel, with an emphasis on outcomes related to obesity.A retrospective chart review of a single surgeon's 2-year URS experience was performed. Of the 55 ureteroscopies for proximal ureteral...
To compare surgical and functional results of both surgical approaches to endoscopic partial nephrectomy. It is currently performed either by the transperitoneal (t) or the retroperitoneal (r) approach.This was a retrospective, matched-pair comparison of 105 patients who underwent either transperitoneal laparoscopic (Graz) or retroperitoneoscopic (Klagenfurt) partial nephrectomy for clinical T1a renal...
To evaluate the efficacy and safety of phosphodiesterase-5 (PDE-5) inhibitors for treating lower urinary tract symptoms secondary to benign prostatic hyperplasia.Randomized controlled trials were identified and extracted from MEDLINE, Embase, Cochrane Central, and relevant reference lists. The database search, quality assessment, and data extraction were independently performed by 2 reviewers. Heterogeneity...
The primary extrapulmonary sugar tumor (PEST) is rare. Up to now, only 16 cases of PEST have been reported, including 5 pediatric cases. We report a renal benign PEST in a 16-year-old boy, which is the first such case to be reported in the pediatric kidney. The tumor was composed of clear and eosinophilic epithelioid cells, growing with nest and pseudoalveolar structure, which can be confused with...
To describe the distribution and implications of prostate-specific antigen velocity (PSAV) by prostate-specific antigen (PSA) in an unselected population. A PSAV >0.35 and >2.0 ng/mL/y have been associated with an increased risk of prostate cancer (CaP) death more than 10 years and 1 year before diagnosis, respectively. It is unknown how frequently PSAVs of this magnitude occur in community...
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