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Different artificial neural networks (ANNs) using total prostate-specific antigen (PSA) and percentage of free PSA (%fPSA) have been introduced to enhance the specificity of prostate cancer detection. The applicability of independently trained ANN and logistic regression (LR) models to different populations regarding the composition (screening versus referred) and different PSA assays has not yet...
To determine the feasibility of bladder preservation using transurethral resection for patients with muscle-invasive cancer and to determine the proportion of patients with muscle-invasive disease who would be eligible for this approach.A retrospective review demonstrated that 327 patients with muscle-invasive bladder cancer were treated in our institution from 1997 to 2002. Resection was repeated...
Some surgeons will not offer a three-piece inflatable penile prosthesis (IPP) to patients who have undergone retropubic surgery because of a perceived increase in intraoperative risk during reservoir placement into the retropubic space.Of 942 consecutive patients undergoing IPP placement from 1986 to 2006, 115 had undergone radical prostatectomy before placement of an American Medical Systems Ultrex...
To investigate the impact of exposure to the phytoestrogen daidzein on erectile function and sexual hormones. The negative effects of phytoestrogens on the male reproductive system, particularly on penile erection, have hardly been evaluated.Thirty adult male Sprague-Dawley rats were equally divided into a normal control group, three experimental groups, and one positive control group. The three experimental...
To establish whether a difference in the clinical outcomes of patients with progressive and primary muscle-invasive bladder cancer exists.The records of patients who had undergone radical cystectomy for bladder urothelial carcinoma from 1990 to 2005 were reviewed. According to our inclusion criteria, 109 patients with primary muscle-invasive tumor (group 1) and 45 patients with progressive tumors...
To evaluate the risks of local recurrence and repeat surgery after nephron-sparing surgery (NSS) in von Hippel-Lindau (VHL) disease to propose a therapeutic strategy to patients.A total of 21 patients with VHL disease and renal tumors were followed up from February 1987 to August 2005. Surgical resection of all tumors was chosen when the largest tumor exceeded a diameter of 30 mm.Of the 21 patients,...
Tubeless percutaneous nephrolithotomy (PCNL) has been successfully performed in selected patients. We assessed its applicability for use without imposing preoperative restrictions.The study consisted of a prospective and consecutive series of 126 patients. Tubeless PCNL was performed when perforation, residual stones, and significant bleeding had been intraoperatively excluded by fluoroscopy, nephroscopy,...
We evaluated 11 currently available biopsy devices using a standard and a novel renal biopsy technique in a porcine model. We then applied our laboratory findings to clinical practice to improve our biopsy results during laparoscopic renal cryoablation procedures.A total of 11 biopsy devices were applied to live porcine renal tissue using two different techniques. In groups 1 and 2, the biopsy devices...
Fluorescence in situ hybridization (FISH) has been reported to have much better sensitivity for the detection of bladder transitional cell carcinoma (TCC) than urine cytology. We comparatively tested cytology, FISH, and the cytokeratin-detection test of urinary bladder cancer (UBC) in routine clinical practice.In a prospective study, FISH, the urinary bladder cancer test (UBC-enzyme-linked immunosorbent...
A 62-year-old man with Gerstmann-Straüssler-Scheinker syndrome, an inherited prion disease, presented after having manually externalized both his testes, including self-castration of his left testis. The left testis was avulsed, along with 12 in. of spermatic cord. Given the patient's hospice status and the wishes of his family, the patient was not taken to the operating room for an inguinal exploration...
It is well known that a relationship exists between vesicoureteral reflux (VUR) and dysfunctional voiding, and the spontaneous resolution rate in older children is lower than the rate in younger children. In this study, we analyzed our experience with biofeedback treatment in older children with confirmed voiding dysfunction and VUR and investigated the effect of this treatment on the reflux resolution...
The incidence of inguinal hernia after radical retropubic prostatectomy (RRP) is high. We speculated that retraction of the vasa deferentia with a retractor might cause stretch injury of the myopectineal orifice and lead to inguinal hernia. In testing this hypothesis, we performed RRP with a modified technique and followed up patients prospectively.From 1993 to 2002, 171 patients underwent RRP with...
More than 85% of men with prostate cancer die of other causes. An effective method is needed to distinguish fatal forms of prostate cancer from benign variants.We performed a retrospective chart review from a medical oncology practice specializing in prostate cancer. All men with negative bone scans, prostate-specific antigen (PSA) level less than 100 ng/mL, adequate records for review, and who started...
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