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Aims: To compare the long-term effects of brief and prolonged therapy with alpha-n 1 interferon for transfusion-associated chronic hepatitis C.Methods: One hundred and sixteen subjects (male/female 4868, mean age 46.9 years) were studied. Sixty patients were randomised to brief treatment (group 1: interferon 5 Mu/msq. t.i.w. for 2 months, then 3 Mu/msq. t.i.w. for 4 months), and 56 to prolonged...
Background/Aims: Different variants of hepatitis C virus might show different susceptibility to interferon α treatment, but it is important to understand whether this difference in sensitivity reflects an association with other factors, such as cirrhosis or age.Methods: We have used an enzyme-linked immunosorbent hepatitis C virus typing assay based upon the detection of antibody in patient's sera...
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