This study evaluated whether four persons (two groups) with developmental disabilities would be able to improve their collaborative pointing performance through a Multiple Cursor Automatic Pointing Assistive Program (MCAPAP) with a newly developed mouse driver (i.e., a new mouse driver replaces standard mouse driver, and is able to intercept/simulate mouse action). The study was performed according to an ABAB design, in which A represented baseline and B represented intervention phases. Data showed that both groups of participants improved their collaborative pointing ability through the use of MCAPAP during the B (intervention) phase. Practical and developmental implications of the findings are discussed.