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We used MCF-7 human breast cancer cells that endogenously express Cav3.1 and Cav3.2 T-type Ca 2+ channels toward a mechanistic study on the effect of EGCG on [Ca 2+ ] i . Confocal Ca 2+ imaging showed that EGCG induces a [Ca 2+ ] i spike which is due to extracellular Ca 2+ entry and is sensitive to catalase and to low-specificity (mibefradil)...
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