Recently, Ben-Amotz et al. found by spectroscopic studies on aqueous mono-ols that hydrophobic interactions are in fact teetering on the edge of random (i.e. ideal) mixing. This means that they observed the dominance of Gmidealover GmE that is due to non-ideality with inter-molecular interactions. This finding assures that both terms GmE and Gmidealare actually operating within the total Gibbs energy, Gm. In thermodynamic studies, it is common to isolate GmE from Gm. While GmE contains all the information about inter-molecular interactions, its variation against an independent variable tends to be subtle. The thermodynamic quantities of higher order derivatives of Gm, however, provide finer more detailed information. By experimentally determining the second and the third derivatives, and numerically or graphically raising derivative to another level, we learned that aqueous solutions consist of three distinctive mole fraction regions in each of which the molecular level scenario of mixing is qualitatively different. Thus, further elucidation of inter-molecular interactions in aqueous solutions requires to isolate the excess quantities first and then concentrate on the appropriate mole fraction range.