An unusual variation of flexor digitorum superficialis was observed during the cadaver dissection. The flexor digitorum superficialis (FDS) had a normal origin and insertion, except to the index finger, where a muscle belly replaced the tendon of FDS. The unusual muscle belly originated as a continuation of FDS tendon in the carpal tunnel and inserted normally into the middle phalanx. A branch of the median nerve innervated the anomalous muscle belly. The anomalous muscle belly described here should be considered in the aetiology of carpal tunnel syndrome.