A novel Fe doped PbO 2 electrode with a high oxygen evolution potential (OEP) and excellent electrochemical oxidation performance was prepared based on Ti/TiO 2 nanotube arrays (TNTs) for p-nitrophenol (p-NP) degradation. Characterized by scanning electron microscope (SEM), linear sweep voltammetry (LSV) and chronoamporometric experiments, the effect of Fe doping amount on the electrode activity was investigated. Fe doping on PbO 2 electrode improved the electrode morphology, OEP, step current and thus the degradation of p-NP. The optimal Fe doped concentration was 0.02M, and the electrode prepared under this condition possessed the highest OEP of 2.7V and p-NP degradation performance. After 90min treatment, the p-NP degradation efficiency reached 100% with similar energy consumption, and the reaction rate constant increased about 4.3 times compared with that of the unmodified one. This Fe doped Ti/TNTs/PbO 2 anode has a more promising application potential in treatment of wastewater containing biorefractory organic pollutants.