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The peroxisome proliferator-activated receptor (PPAR) γ is regarded as a “master regulator” of adipocyte differentiation and is abundantly expressed in adipose. To understand the biological role of PPARγ in adipose, RNA interference (RNAi) of PPARγ should be a powerful tool. 3T3-L1 cell line serves an excellent model to investigate the mechanism of preadipocyte-to-adipocyte differentiation. However,...
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