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Fluctuations and increments of both C 3 and G 3 levels along the human coding sequences were investigated comparing two sets of Xenopus/human orthologous genes. The first set of genes shows minor differences of the GC 3 levels, the second shows considerable increments of the GC 3 levels in the human genes. In both data sets, the fluctuations of C 3 and G ...
With the rapid increases in the amounts of sequence data for prokaryotic genomes, it has become important to develop systems for automated and accurate genome annotation. We present herein a novel ab initio gene identification system, GeneLook, that predicts protein-coding open reading frames (ORFs) with high sensitivity and specificity with no prior knowledge of the sequence composition. The system...
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