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We completely sequenced a 516,013-bp portion of the porcine genome that encompassed a cluster of genes for chemokine (C–C motif) receptors (CC chemokine receptors). We identified genes for six CC chemokine receptors (CCR1, CCR2, CCR3, CCR5, CCR9, and CCRL2) and two other chemokine receptors (CXCR6 and XCR1) in this region. Clarification of the entire structure of the region and the respective genes...
A crucial pre-requisite for large-scale annotation of eukaryotic genomes is the definition of what constitutes a gene. This issue is addressed here in the light of novel and surprising gene features that have recently emerged from large-scale genomic and transcriptomic analyses. The updated operational definition proposed here is: “a gene is a discrete genomic region whose transcription is regulated...
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