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We have isolated a complete cDNA encoding for the mouse erythrocyte protein 4.2 (P4.2). The entire P4.2 cDNA consists of 3465 nt with an open reading frame (ORF) of 691 amino acids. Northern blot analysis of mouse reticulocyte or spleen RNA using the P4.2 cDNA as a probe, detected a 3.5-kb message. The size of the mouse P4.2 cDNA or message that we obtained, appears to be different from those reported...
Polymerase chain reaction analysis revealed four alternatively spliced variants of each of the γ and δ isoforms of calmodulin-dependent protein kinase II (CaM-kinase II) in rabbit liver. Among the four variants of the γ isoform, two were novel ones, designated as CaM-kinase II γ-H and γ-I. The γ-I variant possessed both of the two deletable exons, D2a and D2b, which had never been found together in...
Peroxisome proliferator-activated receptor alpha (PPARα) plays a key role in regulating the catabolic pathway of lipids in response to a variety of compounds named peroxisome proliferators (PPs). The cellular responses to PPs differ among mouse/rat and other species and actualize the study in swine, which show close resemblance to human lipid physiology and metabolism. We have isolated the cDNA containing...
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