In the present study the effect of SO 4 2 - and HPO 4 2 - on ion exchange of Cu 2 + , Fe 3 + and Cr 3 + on natural clinoptilolite is examined under normality of 0.01 N, temperature of 25+/-2 o C and pH 2-2.5 after four days of equilibration. It is observed that Cu 2 + uptake is significantly decreased in the presence of HPO 4 2 - and SO 4 2 . The observed effect is less significant for Fe 3 + and Cr 3 + in the presence of SO 4 2 - and HPO 4 2 - respectively. This could possibly be due to the metal-anion complex formation and the nature and charges of the complex species present. Blank solutions show precipitation in the case of Fe 3 + /HPO 4 2 - solution, leading in complete removal of Fe 3 + from solutions. Precipitation along with ion exchange is resulting in higher removal of Fe 3 + from the solution than ion exchange or precipitation alone. Finally, anion co-removal is significant, reaching 80% for HPO 4 2 - ions.