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Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in females, with a high prevalence. The etiology of this heterogeneous condition remains obscure, and its phenotype expression varies. Two widely cited previous ESHRE/ASRM sponsored PCOS consensus workshops focused on diagnosis (published in 2004) and infertility management (published in 2008), respectively. The present third PCOS...
To identify an appropriate dose for a new contraceptive levonorgestrel intrauterine system (LNG-IUS).Randomized, open-label, three-arm, phase II study.Thirty-seven centers in five European countries.Parous or nulliparous women aged 21–40 years.Treatment with LNG-IUSs with initial in vitro release rates of 12 or 16 μg/d (LNG-IUS12/16) or 20 μg/d (Mirena).Pearl index, bleeding profile, ease/pain of...
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