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To demonstrate whether leptin modulates reproduction by a direct effect within the ovary.Animal model.National Key Laboratory of Infertility.Adult female db/db mice.Adult littermate wild-type (WT) and diabetic (db) leptin receptor (LR) mutant female mice were matched for the allograft of the ovary to construct new genotypic models, respectively. WT mouse received only one ovary from a WT or a db/db...
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