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Extracellular ATP causes 40% stimulation of Mg2+efflux from Ehrlich ascites tumor cells (EATC) incubated under0-transconditions. ATP also causes a threefold increase of arachidonic acid (AA) metabolite release from [3H]AA-preloaded EATC, indicating that, under these experimental conditions, it induces phospholipase A2(PLA2) activation. ATP-induced Mg2+efflux can be prevented by cyclooxygenase inhibition...
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