Monoisotopic natural niobium foils were irradiated with 10 MeV deuteron beam in the Debrecen Cyclotron Laboratory by using the well-established stacked-foil technique. The experimental cross-sections of the deuteron induced nuclear reactions on natural Nb were determined as a part of our systematic study on excitation functions for isotope production, industrial and other applications. A stack of high-purity niobium foils (7.5 μm thick, 13 pieces) was irradiated. The stack was constructed so that it covered the whole energy range from the threshold energy to the maximum bombarding energy. Catcher foils (aluminum, 9 μm) were also used to separate the target foils and to extend the energy degradation. A Ti foil (13.6 μm) at the front was also applied to monitor the beam current.The possible reactions were listed and the earlier data were collected from the literature. Because of the irradiation and measurement technique only the isotopes with half-life greater than 10 min could be seen. To avoid the activity-loss because of the recoil of the produced isotopes from the backside of the Nb foils, the Nb foils were measured in the first step together with the next Al foil. After that, the Nb and/or Al foils were measured separately. So not only the cross-section, but also the implantation yield of the reactions could be determined.From practical point of view one of the most important isotope from the deuteron induced reactions on natural Nb is the 9 3 m Mo (T 1 / 2 =6.85 h), and practically it is the only isotope measurable under 10 MeV deuteron energy. No earlier measured cross-section data were found in the literature. Systematic study was made to avoid interference from other reactions and from neutron activation, which can occur by deuteron splitting.