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Transcription factor NF-κB is associated with inflammatory response and cell survival. Under inactive condition, NF-κB is sequestered in the cytoplasm by an anchor protein, inhibitor of NF-κB (IκB). NF-κB was shown to be activated during ischemic brain injury. In the present study we have investigated the role of NF-κB in ischemic brain injury using a recombinant adenovirus expressing a dominant negative...
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