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Laminins, the major basement membrane glycoproteins, are composed of three subunits. We identified a splice variant of the human laminin α4 subunit transcript containing 21 extra nucleotides. A heptapeptide sequence, MDCPTIS, was inserted close to the two cysteine residues possibly involved in the intersubunit disulfide bonds. Both the authentic α4 subunit (α4A) and the variant with the heptapeptide...
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