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Type 2 diabetes caused by obesity shows autonomic neuropathy. Molecular mechanism involved in enteric neurodegeneration is not clear. Neuronal nitric oxide synthase (nNOS) is one of the important agents involved in gastrointestinal function. Therefore, expression of nNOS in the duodenum LM–MP of type 2 diabetes model mouse was studied. Real time RT-PCR analysis showed reduction in nNOS expression...
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