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The I domains of CD11 are responsible for the binding of ligands and have a unique structure with 6-7 α helixes and 6 β sheets with interconnecting loops. To determine loops recognizing fibrinogen in CD11c I domain, five oligopeptides corresponding to CD11c loops were used to prevent fibrinogen binding to isolated CD11c I domain. The results of the inhibition experiment indicated that all of the loops...
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