In this work, we determine a reliable and transferable molecular force field for the chromophore of the visual pigments. We obtain this field by calculation using potential SPASIBA for a series of retinal conformers. The parameters were established thanks to various experimental information deduced from crystallography and more particularly from molecular vibration spectroscopy (Infra-red and Raman).The reproduction of the experimental spectra of vibrations remains always a criterion of evaluation of the reliability of a force field. If the latter is good, the field can be applied in all confidence to macromolecular blocks to undertake studies in molecular dynamics.