A review of fluorescent ligands for studying 5-HT3 receptors

Martin Lochner; Andrew J. Thompson

doi:10.1016/j.neuropharm.2015.04.002

Invited review
A review of fluorescent ligands for studying 5-HT3 receptors

Martin Lochner, Andrew J. Thompson

Source

Neuropharmacology > 2015 > 98 > C > 31-40

Abstract

The use of fluorescence is a valuable and increasingly accessible means of probing the pharmacology and physiology of cells and their receptors. To date, the use of fluorescence-based methods for 5-HT₃ receptor research has been quite limited and, although a variety of approaches have been described, these are broadly distributed throughout the literature. In this review we condense these findings into a single, accessible source of reference with the hope of promoting the use of these valuable molecular probes.This article is part of the Special Issue entitled ‘Fluorescent Tools in Neuropharmacology’.