Eocene and Miocene alkali basalts were collected from boreholes in the Jiyang Sag of the Bohai Bay Basin with the aim of investigating lithospheric evolution beneath the eastern North China Craton (NCC). These alkali basalts have oceanic island basalt (OIB)-like trace element characteristics and overall depleted Nd–Hf isotopes (ε Nd (t)=2.4–6.3; ε Hf (t)=7.0–10.1), consistent with derivation from slightly enriched asthenosphere. The Miocene (<23Ma) Guantao basalts, like the Miocene basalts in Shandong, have relatively higher concentrations of incompatible trace elements and are more depleted in heavy rare earth elements (HREEs) than the Eocene Shahejie basalts (47–45Ma), indicating a larger proportion of melts derived from the garnet peridotite/pyroxenite. We interpret this difference as resulting from lithospheric thickening. Lithospheric thickness, estimated from the basalt geochemistry, is ~65–85km at ~45Ma and ~85–95km after about 23Ma. This inferred lithospheric thickening beneath the eastern NCC after the end of the Oligocene is consistent with decreasing paleo-heat flow in the Bohai Bay Basin from ~23Ma to the present. The geochemical variations of the Cenozoic basalts in the Jiyang Sag reveal that the lithospheric thinning beneath the eastern NCC was on-going at ~45Ma, but ceased after the end of the Oligocene.