The purpose of this study was to compare the clinical outcomes of total hip arthroplasty in patients who were smokers to patients who were non-smokers. All total hip arthroplasties performed between 2007 and 2009 were reviewed to identify patients who indicated tobacco use. There were 110 smokers who were matched in a 1:2 ratio to 220 non-smoking patients. At a mean follow-up of 51months (range, 24 to 72months), smokers had an overall significantly lower survivorship of 92% (n=9 revisions), compared to 99% (n=2 revisions) in non-smokers. In addition, there were five complications in smokers (one pneumonia, three superficial infections, and one deep peroneal nerve palsy) compared to none in non-smokers. These results indicate that patients who smoke had higher overall revisions and postoperative complications.