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The pathology of these endocrine organs is generally related to over or underproduction of hormones with resultant biochemical and clinical manifestations or a consequence of mass lesions. Hyperplastic processes and both benign and malignant neoplasms may be associated with hyperfunction. Hypofunction is usually a destructive process. An integrated multidisciplinary approach with morphological findings,...
There are two main types of oesophageal cancer, squamous cell carcinoma (SCC) and adenocarcinoma (ACA). SCC usually affects the middle third of the oesophagus and is associated with smoking, alcohol and low socio-economic status. ACA affects the lower third of the oesophagus and is associated with gastro-oesophageal reflux disease. The UK has the highest incidence of ACA in the world and it is rising...
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