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Intergroup 9514 reported promising outcomes with neoadjuvant chemoradiotherapy for large extremity/trunk soft tissue sarcoma (ESTS). One decade later, optimum integration of chemotherapy and radiotherapy into the perioperative management of ESTS remains to be defined.The National Cancer Data Base was used to identify 3422 patients who underwent resection for large (>8cm) high-grade STS between...
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