An anion exchange resin (OH form) is converted to the chemiluminescent anion form with a new reagentN -(β-carboxypropionyl) isoluminol. The anion of interest in the analyte solution displaces the reagent CPIL anion when passing through the resin, then reacts with a H 2 O 2 -Fe(CN) 3 - 6 solution to produce luminescence. The intensity of the CL produced is linearly related to the concentration of the anion in the analyte solution. A new flow injection chemiluminescence ion exchange technique is established, and can be used to determine Cl - . Br - . NO - 2 . NO - 3 . SO 2 - 4 anions, with detection limits from 8.0 x 10 - 7 to 1.4 x 10 - 6 mol . dm - 3 , and linearity over two orders of magnitude.