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Nitric oxide (NO) and taxol are cytotoxic towards leukemia and tumor cells and interfere with the transcription factor NF-κB activity. NO and taxol inhibited NF-κB activity and were cytotoxic to human and murine leukemia cells, but at a different magnitude (30% cell killing and 80% inhibition of NF-κB). Sub-effective concentrations of SNAP and taxol synergized in killing L-1210 cells but either alone...
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