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The rice mutant, TR-1, was previously selected for resistance to growth inhibition by the tryptophan (Trp) analog 5-methyltryptophan (5MT). This mutant has an elevated Trp level. Since anthranilate synthase (AS) catalyzes the first step of Trp biosynthesis and is normally subject to feedback regulation by Trp, alteration of AS causes elevated Trp levels. In this study, we performed a physiological,...
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