The propagation of fatigue cracks under constant amplitude cyclic loading was studied in welded stiffened steel plates. The residual stresses in the stiffened plates were measured using the neutron diffraction strain-scanning technique. A finite element model of the stiffened plate was constructed to simulate the residual stresses by an uncoupled thermal and thermo-mechanical analysis. Both the finite element model and the neutron diffraction measurements indicated that in general the residual stresses were tensile near the welded stiffeners and compressive between the stiffeners and ahead of the starter notch tip. Fatigue testing indicated that the fatigue crack growth rates of the stiffened plates were in general lower than that of a corresponding unstiffened plate, especially near the notch tip where compressive residual stresses existed. Both the finite element method and Green's function predicted the fatigue crack growth rates with reasonable accuracy.