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The objective of this study is to determine which cognitive processes underlying spelling are most affected in the three variants of primary progressive aphasia (PPA): Logopenic variant primary progressive aphasia (lvPPA), Semantic variant primary progressive aphasia (svPPA), and Nonfluent variant primary progressive aphasia (nfvPPA).23 PPA patients were administered The Johns Hopkins Dysgraphia Battery...
Three language production studies indicate that amnesic H.M. produces speech errors unlike everyday slips-of-the-tongue. Study 1 was a naturalistic task: H.M. and six controls closely matched for age, education, background and IQ described what makes captioned cartoons funny. Nine judges rated the descriptions blind to speaker identity and gave reliably more negative ratings for coherence, vagueness,...
During the last decades, many studies have shown that the thalamus is crucially involved in language and cognition. We critically reviewed a study corpus of 465 patients with vascular thalamic lesions published in the literature since 1980. 42 out of 465 (9%) cases with isolated thalamic lesions allowed further neurocognitive analysis.On the neurolinguistic level, fluent output (=31/33; 93.9%), normal...
Faces and voices are key features of human recognition but the way the brain links them together is still unknown. In this study, we measured brain activity using functional magnetic resonance imaging (fMRI) while participants were recognizing previously learned static faces, voices and voice–static face associations. Using a subtraction method between bimodal and unimodal conditions, we observed...
Movement in Parkinson's disease (PD) is strongly influenced by sensory stimuli. Here, we investigated two features of visual stimuli known to affect response times in healthy individuals; the spatial location of an object (the spatial effect) and its action-relevance (the ‘affordance’ effect). Poliakoff et al. (2007) found that while PD patients show normal spatial effects, they do not show an additional...
Previous research has shown that prism adaptation (prism adaptation) can ameliorate several symptoms of spatial neglect after right-hemisphere damage. But the mechanisms behind this remain unclear. Recently we reported that prisms may increase leftward awareness for neglect in a task using chimeric visual objects, despite apparently not affecting awareness in a task using chimeric emotional faces...
Synaesthetes claim to perceive illusory colours when reading alphanumeric symbols so that two colours are said to be bound to the same letter or digit (i.e., the colour of the ink, e.g., black, and an additional, synaesthetic, colour). To explore the neural correlates of this phenomenon, we used a Stroop single-letter colour-naming task and found that distances in colour space between the illusory...
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