American Journal of Otolaryngology
Purpose: To study whether acute otitis media caused by encapsulated or nontypeable Haemophilus influenzae confers cross-reactive protective immunity in an animal model system and to explore the possible involvement of various humoral specific antibodies in protection.Materials and Methods: Rats were intrabullarly challenged with H influenzae type b and two different nontypeable H influenzae strains...
Purpose: The etiology of sinonasal polyps is sometimes obscure. This study was undertaken to evaluate the potential role of arachidonic acid metabolites (AAm) on recurrent polyposis.Materials and Methods: Tissue production of prostaglandin E2 (PGE2), 6-ketoprostaglandin F1-alpha (PGl 2 ), thromboxane A2 (TxA2), and leukotriene C4 (LTC4) by nasal mucosa was determined by radioimmunoassay in...
Second malignant neoplasms are not uncommon in children, especially following multimodality therapy. The incidence of second cancers may approach 12% at 20 years following the initial cancer. Diligent surveillance is mandatory over a patient's lifetime to minimize morbidity and mortality from second malignant neoplasms.
Purpose: The objective of this study is to find the relationship between pure-tone audiometry results and the auditory brainstem response wave abnormalities.Subjects and Methods: The pure-tone audiometry (PTA) and auditory brainstem responses (ABRs) from 22 patients (44 ears) with diagnosed noise-induced permanent hearing loss were studied. Three indices of PTA were average thresholds of 0.5 kHz/,...