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Objectives: To examine the relative incidence of second primary carcinomas in patients who continued smoking compared with those who had ceased smoking.Methods: This is a retrospective study based on review of the Wake Forest University-Baptist Medical Center Tumor Registry for the years 1985 through 2000. Ninety-one patients who had had an index head and neck tumor and who developed a second independent...
Background and Objectives: Marginal mandibulectomy (MM) has been shown to provide an oncologically sound technique with preservation of function and cosmesis. We reviewed our experience with MM and analyzed oncologic and nononcologic complications.Patients and Methods: Retrospective review of patients, with clinical and/or radiological evidence of tumor attached to the mandible without cortical erosion,...
Ameloblastic carcinoma is a rare primary tumor of the maxillofacial skeleton with a distinct predilection for the mandible. These lesions may initially show histologic features of ameloblastoma that dedifferentiate over time. Other ameloblastic carcinomas initially present with morphologic features suggestive of ameloblastoma with areas of epithelial dedifferentiation. We herein report a rare case...
Purpose: To study the effectiveness of AlloDerm (LifeCell Corporation, Branchburg, NJ) as a graft material in underlay tympanoplasty by comparison to autologous fascia in a chronic tympanic membrane perforation animal model.Materials and Methods: Seventeen chinchillas underwent creation of bilateral chronic tympanic membrane perforations over a 6-week period. Twenty-two stable perforations were divided...
Staple-assisted laryngectomy is a unique method previously reported by Lukyanchenko to prevent wound contamination by using a stapling device for suturing pharyngeal defects in total laryngectomy. We have modified his method and applied it to prevent a postoperative pharyngocutaneous fistula in the treatment of intractable aspiration. In contrast to laryngeal cancer patients, a combined use of an...
The appropriate management of labyrinthine fistulae has been debated in the literature for years. After several recent cases of labyrinthine fistulae at our institution, a review of the published data regarding hearing outcome with fistula management was undertaken. Results of this critical review were presented at departmental grand rounds. The grand rounds presentation, data and discussion are presented...
Purpose: The benefits of bilateral cochlear implants (CIs) versus unilateral CIs were evaluated by comparing the Cantonese lexical tone discrimination scores conducted in a quiet environment and against a background noise.Materials and Methods: Four postlingually deafened Cantonese-speaking adults (2 men and 2 women) with bilateral CIs were included in this study. The subjects were their own control...
Purpose: To discuss unusual facial injuries resulting from a bomb blast.Materials and Methods: In March 1997, a bomb consisting of a bag of nails was detonated in a coffee shop in Tel Aviv. Two of the wounded were brought to our level 1 Trauma Center with unique facial injuries. Computed tomography (CT) scan and CT angiogram were performed.Results: The blast occurred to the immediate right of the...
Purpose: The standard treatment for patients with early glottic carcinoma in Israel has been radiotherapy. In recent years, encouraging results with laryngo-microscopic carbon dioxide laser surgery as a treatment for early glottic carcinoma has changed our treatment strategy. We conducted a retrospective study to investigate the results of carbon dioxide laser excisional technique for early glottic...
Purpose: The purpose of the current study was to investigate the efficacy of concomitant oral etoposide and hyperfractionated radiation for patients with unresectable head and neck squamous cell carcinoma.Methods: A prospective nonrandomized phase I-II study was conducted using concomitant oral etoposide (50 mg/d for 13-27 days) and hyperfractionated radiotherapy (1.2 Gy twice daily to a total of...
Purpose: Several materials have been used in the application of mastoid cavity obliteration during surgery for cholesteatoma; however, nothing has won universal acceptance. Through the advancement of tissue engineering, bone morphogenetic protein-2 (BMP-2)/collagen composites have been elucidated as inducers of heterogenic bone formation. This study was performed to investigate whether these composites...
Purpose: To discuss the role of postoperative radiation therapy (RT) for patients with squamous cell carcinoma of the head and neck.Results: Patients with adverse pathologic features have a high likelihood of local-regional recurrence and a decreased probability of survival after surgery alone. Postoperative RT reduces the risk of local-regional failure and probably improves survival. Patients who...
Background: Metal stents have been advocated to manage complicated tracheal stenosis.Objective: The purpose of this investigation is to review the effectiveness of endoscopic placement of tracheal expandable metal stents for complicated tracheal stenosis.Methods: The charts of 6 patients who have undergone placement of metal expandable stents between 1998 and 2000 were reviewed.Results: Initially,...
We present an unusual and a rare case study of a 45-year-old woman who had swallowed a sharp pointed metallic foreign body while eating meat. The foreign body had migrated from the cricopharynx through the parapharyngeal space and penetrated the internal jugular vein over a period of 10 days presenting as a tender neck swelling. The management of this case is discussed here in brief. (Am J Otolaryngol...
We reviewed a series of 45 patients affected by nontuberculous mycobacterial adenitis of the neck observed in the Ear, Nose, and Throat Institute of S. Orsola-Malpighi Hospital-Bologna over a 20-year period between 1981 and 2001. The mean age was 5.5 years. Patients were tested by using the differential Mantoux test, which was the principal diagnostic tool in the case of atypical mycobacterial infections...
Background: Health-Related Quality of Life (HRQL) measures the impact of a pathologic condition on patient's daily life. Besides from disease-related symptoms, it includes a wide spectrum of daily life activities such as physical and social activities, emotional problems, general feeling, and so on. HRQL of patients with nasal diseases is known to correlate only moderately to conventional clinical...
Liposarcoma of the head and neck is rare. Only 12 cases of scalp liposarcoma have been previously reported. In this report, we describe a case of myxoid/round cell liposarcoma in the scalp of a 28-year-old woman. This case report highlights a histologic pattern rarely reported in the head and neck but consistent with the evolving classification of liposarcomas. (Am J Otolaryngol 2003;24:121-127.
Corniculate cartilage subluxation is a pathology that has not been reported in the medical literature. Causing vague pharyngeal symptoms, this disease entity may be overlooked or misdiagnosed as chronic nonspecific pharyngitis, globus pharyngis, or laryngopharyngeal reflux disease. A careful laryngoscopic examination is the key to detect this disorder. In this article, we present a 45-year-old patient...
Bulimia nervosa is a recognized cause of bilateral parotid gland enlargement that may not be appreciated by most otolaryngologists. Classically the parotid enlargement is transient but may be permanent and spectacular. Our review of the published literature revealed only 2 previous cases that have been considered for superficial parotidectomy, along with much debate as to the efficacy of such treatments...
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