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The aim of this study was to develop a lactoferrin (LF)-immobilized titanium (Ti) substrate to enhance the osteoblast activity of MG-63 cells. Ti substrates were first modified through heparin–dopamine (Hep–DOPA) anchorage. Then, LF was immobilized on the Hep–Ti substrates via electrostatic interactions. Hep–Ti substrates, with or without LF, were evaluated by scanning electron microscopy (SEM), X-ray...
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